Sir Samuel Layinka Ayodeji Manuwa, CMG, OBE, M.D. (1903–1976) was a pioneering Nigerian surgeon, Inspector General of Medical Services and former Chief Medical Adviser to the Federal Government of Nigeria.
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He was the first Nigerian to pass the Fellowship of the Royal Colleges of Surgeons
and he obtained the postgraduate Doctor of Medicine degree from the University of Edinburgh in 1934.
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In 1966, he was elected president of the World Federation for Mental Health.
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As Inspector General of Medical Services, he contributed immensely to the establishment of the University College Hospital, Ibadan, the first medical school in Nigeria. He later became a pro-chancellor and chairman of the governing council at the University of Ibadan. Throughout his career, he sought and worked for the improvement of basic health services in the rural areas of Nigeria.
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While practicing as a surgeon, he invented an excision knife to treat tropical ulcers.
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